产品说明
特点和优势
The azido-dPEG®4 contains an azide function on one end of a single molecular weight dPEG® spacer (17.7 Å) and a reactive group on the other end of the spacer. The dPEG® spacer is hydrophilic and non-immunogenic and improves the water solubility of the target molecule while reducing the immunogenicity and increasing the hydrodynamic volume of the target. The acid function may be activated with 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) or N,N′-dicyclohexylcarbodiimide (DCC) for conjugation to an amine. The azide group reacts with an alkyne in the well-known click chemistry reaction. The click chemistry reaction proceeds by copper(I) or ruthenium catalysis or in a strain-catalyzed reaction with certain types of alkyne partners.
法律信息
Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign
基本信息
经验(实验)分子式 | C11H21N3O6 |
分子量 | 291.30 |
MDL编号 | MFCD12406155 |
PubChem化学物质编号 | 329823931 |
NACRES | NA.22 |
产品性质
测定 | >90% |
形式 | solid or viscous liquid |
reaction suitability | reaction type: click chemistry reagent type: cross-linking reagent reaction type: click chemistry |
聚合物结构设计 | shape: linear functionality: heterobifunctional |
运输 | ambient |
储存温度 | −20℃ |
SMILES string | OC(CCOCCOCCOCCOCCN=[N+]=[N-])=O |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |