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Rat Marrow Stromal Cells: RMSC, adult

品牌
Sigma-Aldrich
货号
R492-05A
包装型号
规格纯度
参考价格
7464.78 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Bone marrow is the major blood creating organ, but in addition to supporting hematopoietic growth and differentiation, marrow stromal cells can be induced to produce cells of other connective tissues, such as bone, cartilage, and fat, as well as cells from neuroectodermal (neurons) and endodermal (hepatocytes) lineages. The potential of HMSCs to maintain multipotency and proliferate extensively in vitro provides new avenues for cell-based therapy in the restoration of damaged or diseased tissue.RMSC from Cell Applications, Inc. have been used to demonstrate that TGF-β stimulates production of MCP-1 by vascular smooth muscle cells, which attracts bone marrow stromal cells (Zhang, 2009); and show that their migration can be stimulated by VPA and lithium through HDAC-CXCR4 and GSK-3β-MMP-9, respectively (Tsai, 2010); to investigate the therapeutic potential of marrow stromal stem cells depending on the extracellular matrix properties (Gershlak, 2013; Sullivan, 2014); and demonstrate that combination of low-level laser therapy and transplantation of marrow stromal stem cells results in greater functional recovery after nerve crush injury (Yang, 2013). Finally, HMSC were used to develop methods to direct stem cell differentiation by altering physical topography of the substrate (Brammer, 2011), and to design surface materials to control cell-adhesion properties (Sommani, 2010; Tsuji, 2011)

细胞系来源

Bone Marrow

应用

Blood production, hematopoietic growth and differentiation, pathways of pluripotent cell differentiation into bone, cartilage and fat, connective tissue production,supportive structure, cell production, cell proliferation, cell based therapy, tissue restoration and repair, differentiation, effects of culture conditinos, HLA expression, cytokine production, immunomodulation, clinical trials.

组分

Rat Marrow Stromal Cell Basal Medium that contains 10% FBS and 10% DMSO

质量

Each lot was tested for proper morphology, Population Doublings, Negative for HIV, Hepatitis B, Hepatitis C, mycoplasma, bacteria, and fungi.

制备说明

  • 2nd passage, >500,000 cells in Rat Marrow Stromal Cell Basal Medium that contains 10% FBS and 10% DMSO
  • Can be cultured at least 10 population doublings

传代培养常规

Please refer to the RMSC Culture Protocol.

基本信息

NACRESNA.81

产品性质

生物来源rat bone marrow (Rat bone marrow)
质量水平100
包装pkg of 500,000 cells
生长模式Adherent
形态学stromal
technique(s)cell culture | mammalian: suitable
相关疾病tuberculosis
运输dry ice
储存温度−196℃

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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