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Human Chondrocytes-Rheumatoid Arthritis: HC-RA, adult

品牌
Sigma-Aldrich
货号
402RA-05A
包装型号
规格纯度
参考价格
12880.9 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

HC-RA Human Chondrocytes are derived from human articular cartilage of donors with rheumatoid arthritis (RA). Rheumatoid arthritis is an inflammatory disease that is characterized by overproliferation of synovial cells and their infiltration into adjacent joint tissues, accompanied by gradual destruction of cartilage and bone erosion. Normally, chondrocytes are responsible for producing and maintaining the extracellular matrix of cartilage, but in RA cartilage, the environment is changed significantly due to inflammation and the invasion of other cells. Therefore, HC-RA can be a useful model to study the effects of those changes on chondrocyte biology. In parallel with normal HC, HC-RA can be used to investigate the differences between normal and pathological joints and evaluate potential treatment strategies.

Characterization: Positive for aggrecan after differentiation.

细胞系来源

Cartilage

应用

model to study effects of RA on chondrocytes, investigate differences between normal and pathological joints and evaluate potential treatment strategies

组分

Basal Medium containing 10% FBS & 10% DMSO

制备说明

  • 1st passage, >500,000 cells in Basal Medium containing 10% FBS & 10% DMSO
  • Can be cultured at least 10 doublings

传代培养常规

Please refer to the HC-RA Culture Protocol.

基本信息

NACRESNA.81

产品性质

生物来源human articular cartilage (rheumatoid arthritic)
质量水平100
包装pkg of 500,000 cells
生长模式Adherent
核型2n = 46
形态学chondrocyte
technique(s)cell culture | mammalian: suitable
相关疾病arthritis
运输dry ice
储存温度−196℃

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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