产品说明
免疫原
Recombinant ras-GTPase-activating protein SH3-domain-binding protein
Immunogen Sequence: GI # 5031703, sequence 132-350
应用
Anti-G3BP antibody produced in chicken is suitbale for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
生化/生理作用
Ras GTPase-activating protein-binding protein 1 is an enzyme encoded by the G3BP1 gene in humans. It is a ubiquitously expressed cytosolic 68kDa protein that physically associates with the SH3 domain of GAP and is essential for Ras signaling. The protein binds to RasGAP and is overexpressed in many human cancers. Down regulation of G3BP1 suppresses cell growth and induces apoptosis in HCT116 cells. It acts as a potential anti-cancer drug target implicated in several cellular functions.
外形
Solution in phosphate buffered saline containing 0.02% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| MDL编号 | MFCD02262927 |
| NACRES | NA.41 |
产品性质
| 生物来源 | chicken |
| 质量水平 | 200 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| species reactivity | rat, mouse, human |
| manufacturer/tradename | Genway 15-288-22382A |
| technique(s) | western blot: suitable |
| NCBI登记号 | NP_005745.1 |
| UniProt登记号 | Q13283 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... G3BP1(10146) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
