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Anti-G3BP antibody produced in chicken

品牌
Sigma-Aldrich
货号
GW22382A
规格纯度
affinity isolated antibody, buffered aqueous solution
参考价格
4692 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

免疫原

Recombinant ras-GTPase-activating protein SH3-domain-binding protein
Immunogen Sequence: GI # 5031703, sequence 132-350

应用

Anti-G3BP antibody produced in chicken is suitbale for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

生化/生理作用

Ras GTPase-activating protein-binding protein 1 is an enzyme encoded by the G3BP1 gene in humans. It is a ubiquitously expressed cytosolic 68kDa protein that physically associates with the SH3 domain of GAP and is essential for Ras signaling. The protein binds to RasGAP and is overexpressed in many human cancers. Down regulation of G3BP1 suppresses cell growth and induces apoptosis in HCT116 cells. It acts as a potential anti-cancer drug target implicated in several cellular functions.

外形

Solution in phosphate buffered saline containing 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD02262927
NACRESNA.41

产品性质

生物来源chicken
质量水平200
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
species reactivityrat, mouse, human
manufacturer/tradenameGenway 15-288-22382A
technique(s)western blot: suitable
NCBI登记号NP_005745.1
UniProt登记号Q13283
运输wet ice
储存温度−20℃
Gene Informationhuman ... G3BP1(10146)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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