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Human Marrow Stromal Cells: HMSC, adult

品牌
Sigma-Aldrich
货号
492-05A
包装型号
规格纯度
参考价格
12389.3 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Bone marrow is the major blood creating organ, but in addition to supporting hematopoietic growth and differentiation, marrow stromal cells can be induced to produce cells of other connective tissues, such as bone, cartilage, and fat, as well as cells from neuroectodermal (neurons) and endodermal (hepatocytes) lineages. The potential of HMSCs to maintain multipotency and proliferate extensively in vitro provides new avenues for cell-based therapy in the restoration of damaged or diseased tissue.

HMSC have been utilized to investigate the effects of TGF-β1 on differentiation toward different lineages, and show that it inhibits adipogenic differentiation and induces either chondrogenic, osteogenic or smooth muscle cell differentiation, depending the specific culture conditions (Zhao, 2011); to develop methods to assess differentiation potential of stem cells without the differentiation induction (Hirota, 2011); to compare HLA expression profiles of bone marrow-derived and adipose-derived stem cells (Purandare, 2013); and to design heart valve-shaped tri-layered collagen-based constructs for stem cell seeding and differentiation to use in heart valve tissue engineering (Tedder, 2010, 2011).

细胞系来源

Bone Marrow

应用

blood production, hematopoietic growth and differentiation, pathways of pluripotent cell differentiation into bone, cartilage and fat, connective tissue production,supportive structure, cell production, cell proliferation, cell based therapy, tissue restoration and repair, differentiation, effects of culture conditinos, HLA expression, cytokine production, immunomodulation, clinical trials

组分

Basal Medium containing 10% FBS & 10% DMSO

制备说明

  • 2nd passage, >500,000 cells in Basal Medium containing 10% FBS & 10% DMSO
  • Can be cultured at least 10 doublings

传代培养常规

Please refer to the HMSC Culture Protocol.

基本信息

NACRESNA.81

产品性质

质量水平100
生物来源human bone marrow
包装pkg of 500,000 cells
生长模式Adherent
核型2n = 46
形态学stromal
technique(s)cell culture | mammalian: suitable
相关疾病tuberculosis
运输dry ice
储存温度−196℃

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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