产品说明
一般描述
The pulmonary vasculature is of great physiological/pathological significance. It is now recognized to be a tissue composed of metabolically active, functionally responsive cells, that interact with circulating substrates and regulate the composition of systemic arterial blood, affect target organ functions, and contribute to thrombosis, hemostasis and immune reactions, as well as tumor metastasis. Human Lung Microvascular Endothelial Cells (HLMVEC) provide a useful tool for studying various aspects of pathology and biology of the pulmonary microvasculature in vitro.
HLMVEC have been used to elucidate the therapeutic effects of Angiotensin I-converting enzyme (ACE) inhibitors, and the results revealed that they provide an additional benefit to patients by activating bradykinin B1 receptor leading to prolonged nitric oxide (NO) production in endothelial cells and inhibition of PKCε (Ignjatovic, 2004; Stanisavljevic, 2006).
细胞系来源
Lungs
应用
lung physiology, metabolism, regulate blood composition, hemostasis, immune reactions, therapeutic effects, leukocyte migration,
组分
Cell Basal Medium containing 10% FBS & 10% DMSO
制备说明
- 3rd passage, >500,000 cells in Cell Basal Medium containing 10% FBS & 10% DMSO
- Can be cultured at least 15 doublings
传代培养常规
Please refer to the HLMVEC Culture Protocol.
基本信息
| NACRES | NA.81 |
产品性质
| 生物来源 | human lung (normal) |
| 质量水平 | 100 |
| 包装 | pkg of 500,000 cells |
| 生长模式 | Adherent |
| 核型 | 2n = 46 |
| 形态学 | Endothelial |
| technique(s) | cell culture | mammalian: suitable |
| 相关疾病 | metastasis |
| 运输 | dry ice |
| 储存温度 | −196℃ |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
