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Asiatic Acid

亚细亚酸

品牌
Sigma-Aldrich
CAS
464-92-6
货号
A2612
规格纯度
≥98% (HPLC), from Centella asiatica
参考价格
3222.94 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Asiatic acid is a naturally occurring pentacyclic triterpenoid, obtained from Centella asiatica.

应用

积雪草酸衍生物合成的起始物料:

  • 抗癌药
  • 糖原磷酸化酶抑制剂
  • 肝保护剂

Asiatic acid has been used in the in vitro study of its cytotoxic potential in glioblastoma cells. It has also been used for the in vivo quantitative analysis of asiatic acid in Centella asiatica L. and in vitro study of enhancement of asiatic acid yield upon using organic elicitors.

包装

10 mg in glass bottle
50 mg in poly bottle

生化/生理作用

Asiatic acid has been reported to exhibit a pernicious effect on glioblastoma, breast, liver, melanoma, and colon cancers and anti-angiogenic activity. Additionally, it can cross the blood-brain barrier and cause apoptosis in human malignant glioma and hepatoma cells. Asiatic acid also effectively inhibits the Ultraviolet A modulated signal transduction pathways and thereby can be used against UVA-induced photoaging of the skin. It has been noted to show antinociceptive and anti-inflammatory properties plus inhibitory effect on neurotoxicity induced by β-amyloid and glutamate.
积雪草酸常用于伤口愈合。积雪草酸具有抗氧化、抗炎和神经保护属性

基本信息

经验(实验)分子式C30H48O5
分子量488.70
EC 号482-720-9
MDL编号MFCD00238541
PubChem化学物质编号329770790
NACRESNA.25

产品性质

质量水平200
生物来源Centella asiatica
测定≥98% (HPLC)
形式powder
储存条件protect from light
颜色 white
mp325-330 ℃ (lit.)
溶解性methanol: 1 mg/mL, clear, colorless
储存温度2-8℃
SMILES stringC[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)[C@@H]5CC[C@@]34C)[C@@H]2[C@H]1C)C(O)=O
InChI1S/C30H48O5/c1-17-9-12-30(25(34)35)14-13-28(5)19(23(30)18(17)2)7-8-22-26(3)15-20(32)24(33)27(4,16-31)21(26)10-11-29(22,28)6/h7,17-18,20-24,31-33H,8-16H2,1-6H3,(H,34,35)/t17-,18+,20-,21-,22-,23+,24+,26+,27+,28-,29-,30+/m1/s1
InChI keyJXSVIVRDWWRQRT-UYDOISQJSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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