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γ-Aminobutyric acid

4-氨基丁酸

品牌
Sigma-Aldrich
CAS
56-12-2
货号
A5835
规格纯度
BioXtra, ≥99%
参考价格
710 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

γ-Aminobutyric acid (GABA) is a non-protein amino acid associated with the brain. Being synthesized in the nervous system, it is packed into synaptic vesicles. It is present naturally in green tea, soybean, germinated rice, and in some fermented foods.

应用

γ-Aminobutyric acid (GABA) has been used to treat dorsal root ganglion neurons for electrophysiological recordings studies to test its effect on neuropathic pain in rats. It has also been used to test its protective effects in an ex vivo machine perfusion system of small-for-size grafts (SFSG) injury model.

包装

10 mg in autosample vial

生化/生理作用

γ-Aminobutyric acid (GABA) is a mammalian inhibitory neurotransmitter with multiple functions. It is crucial for the normal central nervous system (CNS) functioning. A few documented functions of GABA include its protective role in toxin-induced damage. It also elicits anti-hypertensive, anti-diabetic, anti-microbial, antioxidant, anti-allergy, anti-inflammatory, and anti-cancer effects. GABA might show beneficial effects on stress and sleep in humans. γ-Aminobutyric acid (GABA) is used to study the biological and biochemical processes mediated via the GABA receptors, GABAA and GABAB.
大脑中的主要抑制性神经递质;GABAA 和 GABAB 受体激动剂;增加 Cl 的传导性。

基本信息

线性分子式NH2(CH2)3COOH
分子量103.12
Beilstein906818
EC 号200-258-6
MDL编号MFCD00008226
PubChem化学物质编号24891025
NACRESNA.26

产品性质

质量水平200
产品线BioXtra
测定≥99%
形式powder
technique(s)ligand binding assay: suitable
杂质<0.0005% Phosphorus (P)
<0.1% Insoluble matter
灼烧残渣<0.1%
颜色 white
mp195 ℃ (dec.) (lit.)
溶解性H2O: 0.5 M at 20 ℃, clear, colorless
痕量阴离子chloride (Cl-): <0.04%
sulfate (SO42-): <0.05%
痕量阳离子Al: <5 mg/kg
Ca: <20 mg/kg
Cu: <5 mg/kg
Fe: <5 mg/kg
K: <50 mg/kg
Mg: <50 mg/kg
NH4+: <500 mg/kg
Na: <70 mg/kg
Pb: <10 mg/kg
Zn: <5 mg/kg
SMILES stringNCCCC(O)=O
InChI1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)
InChI keyBTCSSZJGUNDROE-UHFFFAOYSA-N
Gene Informationhuman ... SLC6A1(6529), SLC6A11(6538), SLC6A12(6539)
rat ... Gabra1(29705), Gabra2(29706), Olr1750(294204), Slc6a1(79212), Slc6a12(50676)

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves

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