产品说明
一般描述
This support is useful for the production of peptide aldehydes and other carboxaldehydes. Following removal of the Fmoc group with 20% piperidine in DMF, acylation of the resin-bound methoxylamine is best effected using DIPCDI/HOAt or HATU/DIPEA activation. This results in formation of a supported Weinreb-type amide which can be either reduced to an aldehyde with LiAlH4 [1, 2] or cleaved with Grignard reagents to give ketones [2, 3].
The product number for this product was previously 01-64-0153.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.
联系
Replaces: 01-64-0153
分析说明
Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.40 - 1.00 mmol/g
Swelling Volume (in CH₂Cl₂): lot specific result
The polymer matrix is copoly (styrene - 1 % DVB), 100 - 200 mesh
法律信息
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
产品性质
| 质量水平 | 200 |
| 产品线 | Novabiochem® |
| 形式 | beads |
| reaction suitability | reaction type: Fmoc solid-phase peptide synthesis |
| manufacturer/tradename | Novabiochem® |
| application(s) | peptide synthesis |
| 储存温度 | 2-30℃ |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
