产品说明
一般描述
This resin is a useful tool for the synthesis of peptide aldehydes [1]. Attachment of pre-formed amino acid aldehydes to this resin is effected by heating in 1% DIPEA in MeOH at 60 °C. Following chain extension using standard protocols, side-chain protecting groups can be removed with anhydrous TFA, prior to cleavage of the fully deprotected peptide aldehyde with MeCN/water/TFA.
An analogous resin has been recently used to capture and purify peptide aldehydes generated by oxidation of peptide alcohols with IBX-polystyrene [2].
Novabiochem′s pre-loaded amino aldehyde resins can be found on page x.
The product number for this product was previously 04-12-3710.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.
联系
Replaces: 04-12-3710
分析说明
Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (determined from the substitution of the Fmoc- Oxybenzaldehyde loaded resin): 0.15 - 0.35 mmol/g
Identity (of the substitution): passes test
Swelling Volume (in DMF): lot specific result
The base resin is amino PEG-PS-copolymer (90 µm).
法律信息
NOVASYN is a registered trademark of Merck KGaA, Darmstadt, Germany
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
产品性质
| 质量水平 | 200 |
| 产品线 | NovaSyn® TG Novabiochem® |
| 形式 | beads |
| reaction suitability | reaction type: Fmoc solid-phase peptide synthesis reactivity: carbonyl reactive |
| manufacturer/tradename | Novabiochem® |
| 官能团 | amine |
| 储存温度 | 2-8℃ |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
