产品说明
一般描述
Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the ′beads on a string′ structure.
The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.
特异性
H3 phosphorylated at Thr3
免疫原
synthetic peptide containing, in which pT corresponds to phosphothreonine at position 3 of human Histone H3
应用
Anti-phospho-Histone H3 (Thr3) Antibody is a Rabbit Polyclonal Antibody for detection of phospho-Histone H3 (Thr3) also known as H3T3P, Histone H3 (phospho T3) & has been validated in IF, WB, ICC.
Research Sub Category
Histones
Research Category
Epigenetics & Nuclear Function
质量
routinely evaluated by immunoblot in acid extracted proteins from mitotic HeLa cells
目标描述
17 kDa
外形
Format: Unpurified
0.05% sodium azide and 30% glycerol.
Immunodepleted
储存及稳定性
2 years at -20°C
分析说明
Control
Acid extract from colcemid-treated HeLa cells
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | unpurified |
antibody product type | primary antibodies |
克隆 | polyclonal |
species reactivity | human |
manufacturer/tradename | Upstate® |
technique(s) | immunocytochemistry: suitable immunofluorescence: suitable western blot: suitable |
NCBI登记号 | NM_003493 |
UniProt登记号 | Q16695 |
运输 | dry ice |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |