产品说明
一般描述
Histone H3 is one of the 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N terminal tail H3 is involved with the structure of the nucleosomes of the ′beads on a string′ structure.
Acetylation of histone H3 occurs at several different lysine positions in the histone tail and is performed by a family of enzymes known as Histone Acetyl Transferases (HATs).
特异性
Broad species cross-reactivity expected
Recognizes Histone H3 acetylated on lysines 9 and 18.
免疫原
peptide (ARAcKSTGGKAPRAcKQL) which corresponds to acetyl-lysine at residue 9 and 18 of human Histone H3
应用
Anti-acetyl-Histone H3 (Lys9/18) Antibody is a rabbit polyclonal antibody for detection of acetyl-Histone H3 (Lys9/18) also known as H3K9/18Ac, Histone H3 (acetyl K9/18) & has been validated in ChIP, WB, Mplex.
Research Sub Category
Histones
Research Category
Epigenetics & Nuclear Function
质量
routinely evaluated by immunoblot on acid extracts from sodium butyrate treated Hela cells (Catalog #17-305)
目标描述
17 kDa
外形
Protein A Purified immunoglobulin in 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.105 M NaCl, 0.035% sodium azide as a preservative.
Unpurified
储存及稳定性
Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
分析说明
Control
Acid extracts from sodium butyrate treated HeLa cells
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 抗体形式 | serum |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| species reactivity | human, Saccharomyces cerevisiae, bovine, mouse |
| manufacturer/tradename | Upstate® |
| technique(s) | ChIP: suitable multiplexing: suitable western blot: suitable |
| 同位素/亚型 | IgG |
| NCBI登记号 | NM_003493 |
| UniProt登记号 | Q16695 |
| 运输 | wet ice |
| Gene Information | human ... H3F3B(3021) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
