产品说明
一般描述
Type 1 protein Ser/Thr phosphatases (PP1) have a high specific activity against phosphorylase, and are resistant to okadaic acid up to concentrations of 50 nM, but sensitive to Inhibitor-2 and microcystin LR.
特异性
Recognizes Protein Phosphatase 1γ1. No cross reactivity with other recombinant PP1 isoforms.
免疫原
The immunogen used to the purified peptide conjugated to KLH corresponding to the to the C –terminus of PP1 gamma 1 catalytic subunit (amino acids 311-323).
Epitope: C-terminus
应用
Immunoprecipitation: A previous lot of this antibody was used on Immunoprecipitation.
Anti-PP1γ1 Antibody detects level of PP1γ1 & has been published & validated for use in WB & IP.
Research Category
Signaling
Research Sub Category
Kinases & Phosphatases
质量
Routinely evaluated by Western Blot on HeLa lysates.
Western Blot Analysis: 1:500 dilution of this lot detected PP-1 GAMMA on 10 μg of HeLa lysates.
目标描述
~37 kDa
联系
Replaces: AB4084
外形
Purified
Purified rabbit polyclonal IgG provided as 0.2µm sterile filtered solution in phosphate buffered saline with 0.08% sodium azide.
Format: Purified
储存及稳定性
Maintain at -20°C in undiluted aliquots for up to 1 year from date of receipt.
Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
分析说明
Control
HeLa Cell Lysate
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 抗体形式 | affinity purified immunoglobulin |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| species reactivity | rat, bovine, mouse, human |
| manufacturer/tradename | Upstate® |
| technique(s) | immunoprecipitation (IP): suitable western blot: suitable |
| 同位素/亚型 | IgG |
| NCBI登记号 | NM_002710.1 |
| UniProt登记号 | P36873 |
| 运输 | wet ice |
| Gene Information | human ... PPP1CC(5501) |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
