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C3d Rabbit Polyclonal Antibody

品牌
Sigma-Aldrich
货号
403A-7
包装型号
规格纯度
参考价格
2573.11 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. C3d deposition in the renal transplant PTCs (peritubular capillaries) is indicative of AR (acute rejection) with subsequent high probability of graft loss. Anti-C3d, combined with anti-C4d, can be utilized as a tool for diagnosis of AR and warrant prompt and aggressive anti-rejection treatment.

In another study, Pfaltz et al. have shown that anti-C3d labeled the epidermal basement membrane in 97% (31/32) cases of bullous pemphigoid (BP), with none of the normal controls demonstrating such findings. In the same study 27% (3/11) cases of pemphigus vulgaris (PV) demonstrated intercellular C3d deposition. Therefore, C3d immunohistochemistry is a helpful adjunct in the diagnosis of BP (and perhaps PV), especially in the cases in which only formalin-fixed, paraffin embedded tissue is available for analysis.

质量


IVD

IVD

IVD

RUO

联系

C3d Positive Control Slides, Product No. 403S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外形

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

制备说明

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其他说明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律信息

Cell Marque is a trademark of sigma-aldrich Co. LLC

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平500
100
偶联物unconjugated
抗体形式Ig fraction of antiserum
antibody product typeprimary antibodies
克隆polyclonal
描述For In Vitro Diagnostic Use in Select Regions (See Chart)
形式buffered aqueous solution
species reactivityhuman
包装vial of 0.1 mL concentrate (403A-74)
vial of 0.5 mL concentrate (403A-75)
bottle of 1.0 mL predilute (403A-77)
vial of 1.0 mL concentrate (403A-76)
bottle of 7.0 mL predilute (403A-78)
manufacturer/tradenameCell Marque
technique(s)immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
运输wet ice
储存温度2-8℃
可视化cytoplasmic, membranous

Sigma-Aldrich

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