产品说明
一般描述
Nitrotyrosine has been identified as an indicator of cell damage and inflammation, as well as of the production of NO. It is believed that measuring the concentration of nitrotyrosine will serve as a marker for damage caused by NO in the cell. Previous studies have shown that nitrotyrosine has been found in inflammatory conditions such as atherosclerotic plaques and rheumatoid arthritis, among others.
特异性
Recognizes proteins which are nitrated.
免疫原
Nitrated KLH
应用
Research Sub Category
Neurotransmitters & Receptors
Neurodegenerative Diseases
This Anti-Nitrotyrosine Antibody is published in more than 80 citations and validated for use in Immunocytochemistry (IC), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blotting (WB) for the detection of Nitrotyrosine.
Research Category
Neuroscience
质量
routinely evaluated by immunoblot on nitrotyrosine immunoblotting controls (Catalog #12-354)
目标描述
Predicted MW for nitrated-BSA: 85 kDa
外形
ImmunoAffinity Purified
Purified Rabbit IgG in buffer containing 0.1M Tris-Glycine, 0.15M NaCl, pH 7.4, 0.05% sodium azide, and 10 mg/mL BSA
Format: Purified
储存及稳定性
Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
分析说明
Control
Immunohistochemistry: Human Alzheimer disease brain sections; mouse liver
Immunoblotting: Nitrated-BSA
Indirect ELISA: Nitrated-BSA
Indirect immunofluorescence: A549 cells metabolically labeled with 3-nitrotyrosine
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 抗体形式 | affinity purified immunoglobulin |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| species reactivity (predicted by homology) | all |
| manufacturer/tradename | Upstate® |
| technique(s) | immunocytochemistry: suitable immunohistochemistry: suitable immunoprecipitation (IP): suitable western blot: suitable |
| 同位素/亚型 | IgG |
| 运输 | dry ice |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
