Anti-Frizzled 5 Antibody

产品说明

一般描述

The Wnt family consists of ligands involved in cell fate determination, organogenesis, and oncogenesis. The Wnt signal is thought to be transduced sequentially via a homolog of the frizzled family of receptors to GSK-3 (disheveled), β- and γ- catenin and finally to members of the Tcf/Lef-1 family of HMG box transcription factors. Frizzled 5 is believed to function as the receptor for the Wnt5a ligand.

特异性

Frizzled 5 (aka Fz5 or Fzd5)

免疫原

Epitope: C-Terminus
KLH-conjugated, synthetic peptide derived from amino acids 564-585 of human Frizzled 5 (CTGRTPPGPAATYHKQVSLSHV).

应用

Research Sub Category
Developmental Signaling

GPCR, cAMP/cGMP & Calcium Signaling
Research Category
Signaling
Anti-Frizzled 5 Antibody is an antibody against Frizzled 5 for use in WB.

质量

Routinely evaluated by immunoblot on lysates from mouse liver, C2C12, Jurkat or HUVEC cells

目标描述

Frizzled 5 (62kDa)

外形

Protein A chromatography
Format: Purified
Purified antibody in PBS with 0.05% sodium azide and 30% Glycerol

储存及稳定性

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

分析说明

Control
Lysates from mouse liver, C2C12, Jurkat, and HUVEC

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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