产品说明
一般描述
Monoclonal Anti-Pontin (mouse IgG1 isotype) is derived from the hybridoma 5G3-11 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a human pontin fusion protein. Pontin and reptin are two related members of the AAA+ (ATPases associated with diverse cellular activities) family of ATPases. Pontin and reptin share some homology to the bacterial RuvB gene.
免疫原
human Pontin fusion protein
应用
Monoclonal Anti-Pontin antibody produced in mouse has been used in:
- western blotting
- immunoprecipitation
- ChIP-sequencing
- immunohistochemistry
- immunofluorescence
- RNA immunoprecipitation
生化/生理作用
Pontin and Reptin are associated with several chromatin-remodeling complexes and are involved in multiple biological processes including chromatin remodeling, DNA damage repair, transcriptional regulation, telomerase activity, apoptosis and cancer metastasis. Both proteins are also involved in cellular transformation by beta-catenin and c-myc through their chromatin remodeling function.
外形
Solution in 0.01 M phosphate buffered saline, 7.4 pH, containing 15 mM sodium azide
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 质量水平 | 200 |
| 生物来源 | mouse |
| 偶联物 | unconjugated |
| 抗体形式 | purified from hybridoma cell culture |
| antibody product type | primary antibodies |
| 克隆 | 5G3-11, monoclonal |
| 形式 | buffered aqueous solution |
| 分子量 | ~50 kDa |
| species reactivity | monkey, human, canine |
| technique(s) | immunohistochemistry immunoprecipitation (IP) indirect immunofluorescence western blot |
| 同位素/亚型 | IgG |
| UniProt登记号 | Q9Y265 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... RUVBL1(8607) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
