产品说明
一般描述
FOXO1 (forkhead box O1) is encoded by the gene mapped to human chromosome 13q14. The encoded protein is a transcription factor and is a member of the Foxo subfamily.
免疫原
Peptide sequence around phosphorylation site of serine 256 (A-A-S(p)-M-D), according to the protein FOXO1.
应用
Anti-phospho-FOXO1 (pSer256) antibody produced in rabbit has been used in western blotting.
生化/生理作用
FOXO1 (forkhead box O1) blocks the differentiation of cell in fetal pancreatic progenitor cells. It controls the differentiation of adipocytes. FOXO1 is involved in the insulin regulation of glucose-6-phosphatase (G6p) expression. Additionally, this protein plays a vital role in tumor suppression by inducing growth arrest and apoptosis.
特点和优势
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目标描述
Transcription factor.
外形
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| MDL编号 | MFCD03791549 |
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 78-82 kDa |
| species reactivity | mouse, rat, human |
| 浓度 | 1 mg/mL |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 indirect immunofluorescence: 1:100-1:200 western blot: 1:500-1:1000 |
| 同位素/亚型 | IgG |
| 免疫原序列 | (A-A-SP-M-D) |
| NCBI登记号 | NP_002006.2 |
| UniProt登记号 | Q12778 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... FOXO1(2308) |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
