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Anti-HMGA2 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB2701959
包装型号
规格纯度
参考价格
5683.7 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

High mobility group A2 (HMGA2) protein is a non-histone architectural transcription factor. This protein belongs to the high-mobility group adenine/thymine (AT)-hook (HMGA) family. HMGA2 is expressed in the mesenchyme prior differentiation and tumors of epithelial origin. The HMGA2 gene is located on the human chromosome at 12q14.3.

免疫原

Recombinant fragment corresponding to a region within amino acids 1 and 109 of HMGA2 (Uniprot ID#P52926)

应用

Anti-HMGA2 antibody produced in rabbit has been used in immunohistochemistry (1:250), (1:100), (1:4000).

生化/生理作用

High mobility group A2 (HMGA2) protein is involved in regulating the activity of various genes by binding to the adenine/thymine (AT)-rich sequences present in the minor groove of B‑form DNA. This protein plays a role in many biological processes such as the DNA damage repair process, senescence, apoptosis, and cell cycle process. HMGA2 protein also plays a role in epithelial-mesenchymal transition and telomere restoration. Overexpression of HMG2A gene is observed in metastatic lung adenocarcinoma.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆polyclonal
形式liquid
分子量 12 kDa
species reactivityrat, human, mouse
浓度0.7 mg/mL
technique(s)ChIP: suitable
immunofluorescence: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
immunoprecipitation (IP): suitable
western blot: 5000-50000
UniProt登记号P52926
运输wet ice
储存温度−20℃
Gene Informationhuman ... HMGA2(8091)

安全信息

象形图GHS07
警示用语:Warning
危险声明H317 - H412
预防措施声明P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
危险分类Aquatic Chronic 3 - Skin Sens. 1
储存分类代码12 - Non Combustible Liquids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

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