产品说明
一般描述
The TNNI3K (TNNI3 interacting kinase) gene is a novel cardiac troponin I-interacting kinase gene and is mapped to human chromosome 1p31.1. The gene is expressed in cardiomyocytes. The encoded protein belongs to mitogen-activated protein kinase kinase kinase (MAPKKK) family. Tnni3k consists of seven to ten ankyrin repeats at the N terminal, a Ser/Thr and Tyr kinase domain, and a Ser-rich domain at the C-terminal.
Anti-TNNI3K antibody detects endogenous levels of total TNNI3K protein.
免疫原
The antiserum was produced against synthesized peptide derived from human TNNI3K.
Immunogen Range: 301-350
生化/生理作用
Overexpression of TNNI3K (TNNI3 interacting kinase) may induce and increase cardiac myogenesis and performance respectively. It also might inhibit ventricular remodeling, caused by ischemia. TNNI3K might be associated with the development of cardiac hypertrophy. TNNI3K is known to be associated with atrioventricular conduction disease, acute coronary syndrome and obesity.
特点和优势
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外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen 104 kDa |
| species reactivity | human, mouse, rat |
| 浓度 | ~1 mg/mL |
| technique(s) | ELISA: 1:10000 immunohistochemistry: 1:50-1:100 |
| NCBI登记号 | Q59H18 |
| UniProt登记号 | Q59H18 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... TNNI3K(51086) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | nwg |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
