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Anti-RNASET2 Antibody

品牌
Sigma-Aldrich
货号
ABF293
规格纯度
from rabbit, purified by affinity chromatography
参考价格
6022.61 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Ribonuclease T2, also known as Ribonuclease 6, and encoded by the gene name RNASET2 or RNASE6PL, is a novel member of the Rh/T2/S-glycoprotein class of extracellular ribonucleases. It is a single copy gene that maps to 6q27, a region associated with human malignancies and chromosomal rearrangement, and has been suggested to function as a tumor suppressor protein. Its expression is suppressed in Human T-cell Leukemia Virus type 1 (HTLV-1) infected cells following the binding of the HTLV-1 Tax protein to the RNASET2 promoter. As Adult T-cell leukemia (ATL) is one of the primary diseases caused by HTLV-1 infection, a reduction in the level of RNASET2 by Tax may play a role in ATL development.

免疫原

KLH-conjugated synthetic peptide corresponding to the C-terminus of human RNASET2.
Epitope: C-terminus

应用

Research Sub Category
Inflammation & Autoimmune Mechanisms
Anti-RNASET2 Antibody detects level of RNASET2 & has been published & validated for use in RNASET2.
Research Category
Inflammation & Immunology

质量

Evaluated by Western Blotting in SW480 cell lysate with and without blocking peptide.

Western Blotting Analysis: 2 μg/mL of this antibody detected RNASET2 in SW480 cell lysate with and without blocking peptide.

目标描述

~40 kDa observed. Uncharacterized bands may be observed in some lysate(s). Uniprot describes 2 isoforms produced by alternative splicing at ~40 kDa, ~14 kDa, and ~29 kDa

外形

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Antigen Affinity Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

生物来源rabbit
质量水平100
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
纯化方式affinity chromatography
species reactivityhuman
technique(s)western blot: suitable
UniProt登记号O00584
运输wet ice

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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