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Anti-PLAUR/uPAR antibody, Mouse monoclonal

单克隆抗 PLAUR/uPAR 小鼠抗

品牌
Sigma-Aldrich
货号
SAB4200412
规格纯度
clone PL231, purified from hybridoma cell culture
参考价格
5045.46 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Plasminogen activator, urokinase receptor (PLAUR) is a well-characterized receptor for matrix-degrading proteases. It is encoded by the gene mapped to human chromosome 19q13.31.

免疫原

peptide corresponding to a sequence at the C-terminus of human PLAUR/uPAR.

应用

Monoclonal Anti-PLAUR/uPAR antibody produced in mouse has been used in Western blotting (WB).

生化/生理作用

Plasminogen activator, urokinase receptor (PLAUR) plays a vital role in tumor cell invasion, angiogenesis and metastasis. It acts as a key regulator of cell-surface plasminogen activator. It is implicated in various normal and pathological processes. Elevated expression of the gene has been observed in various types of cancers, including head and neck squamous cell carcinoma (HNSCC). Thus, it is considered as an potent biomarker for targeted imaging or therapy. Upregulated expression of PLAUR leads to the progression of kidney disease in children.

外形

0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

质量水平200
生物来源mouse
偶联物unconjugated
抗体形式purified from hybridoma cell culture
antibody product typeprimary antibodies
克隆PL231, monoclonal
形式buffered aqueous solution
分子量antigen ~55 kDa
species reactivitymonkey, human, mouse, rat, canine
浓度~1.0 mg/mL
technique(s)indirect immunofluorescence: suitable
western blot: 4.0-8.0 μg/mL using extracts of HL-60 cells
同位素/亚型IgG1
UniProt登记号Q03405
运输dry ice
储存温度−20℃
Gene Informationhuman ... PLAUR(5329)

安全信息

储存分类代码10 - Combustible liquids
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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