产品说明
一般描述
Human Insulin-like Growth Factor 2 (IGF2) contains 67 amino acids and shares similar structural features with IGF1, including a 62% sequence homology. In human plasma, IGF1 and IGF2 are associated with IGF-binding proteins that transport the polypeptides and partially regulate their actions in vivo. In addition to the insulin receptor, IGF2 binds to two forms of IGF receptors, both of which are widely distributed in different tissues and cultured cells. IGF2 is mitogenic for a variety of cultured cells, including mouse 3T3 cells,12 normal rat kidney cells, human or chicken fibroblasts and MCF-7 human breast carcinoma cells.
免疫原
KLH-conjugated linear peptide corresponding to the human Insulin-like growth factor 2 mature chain.
Epitope: Insulin-like growth factor 2 mature chain
应用
This Anti-IGF2 Antibody is validated for use in Western Blotting for the detection of IGF2.
Research Sub Category
Apoptosis - Additional
Research Category
Apoptosis & Cancer
质量
Evaluated by Western Blotting in human placenta tissue lysate.
Western Blotting Analysis: A 1:500 dilution of this antibody detected IGF2 in 10 µg of human placenta tissue lysate.
目标描述
~24 kDa observed. This antibody detects all 3 isoforms of IGF2 (20-26 kDa), and may run higher than expected due to glycosylation.
外形
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Affinity purified
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
其他说明
Concentration: Please refer to lot specific datasheet.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
纯化方式 | affinity chromatography |
species reactivity | human |
technique(s) | western blot: suitable |
NCBI登记号 | NP_000603 |
UniProt登记号 | P01344 |
运输 | wet ice |
Gene Information | human ... IGF2(3481) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |