产品说明
一般描述
Myogenin belongs to the basic helix-loop-helix (bHLH) superfamily.
Myogenin is a transcription factor present in the nucleus. It possesses an amino-acid rich region and a helix-loop-helix structure. The gene encoding it is localized on human chromosome 1q31-41 and has three exons.
免疫原
rat recombinant myogenin (amino acids 30-224).
应用
Monoclonal Anti-Myogenin antibody produced in mouse has been used in immunohistochemistry, immunofluorescence and western blotting.
生化/生理作用
Myogenin acts as a biomarker in rhabdomyosarcoma (RMS). It has a role in developmental processes, such as hematopoiesis, neurogenesis, myogenesis, tumor cell invasion and metastasis.
Myogenin acts as a regulator during myoblast and skeletal muscle differentiation. It is considered as a definite marker for skeletal muscle differentiation.
外形
Solution in phosphate buffered saline containing 0.08% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| MDL编号 | MFCD01322371 |
| NACRES | NA.41 |
产品性质
| 质量水平 | 200 |
| 生物来源 | mouse |
| 偶联物 | unconjugated |
| 抗体形式 | purified immunoglobulin |
| antibody product type | primary antibodies |
| 克隆 | F12B, monoclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen 34 kDa |
| species reactivity | mouse, rat, human |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1-2 μg/mL using rhabdomyosarcoma tissue sections immunoprecipitation (IP): 2 μg using 1 mg protein lysate indirect ELISA: suitable indirect immunofluorescence: suitable western blot: 1 μg/mL |
| 同位素/亚型 | IgG1 |
| UniProt登记号 | P15173 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... MYOG(4656) mouse ... Myog(17928) rat ... Myog(29148) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | nwg |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
