Anti-Achaete-scute homolog 1 Antibody (ASCL1)

产品说明

一般描述

Achaete-scute homolog 1 (ASCL1), also known as MASH1, ASH1 or HASH1, is a basic helix-loop-helix transcription factor. ASCL1 binds to the E box (5′-CANNTG-3′) which then activates transcription. For efficient DNA binding, dimerization with other BHLH proteins is required. Achaete Scute proteins may also be involved in the determination of neuronal precursors in the central and peripheral nervous systems. It is expressed in fetal brain and is essential for the proper development and the survival of subsets of autonomic neurons. It is highly expressed in medullary thyroid cancer and small cell lung cancer.

免疫原

BCP-conjugated linear peptide corresponding to human Achaete-scute homolog 1 (ASCL1).

应用

Western Blotting Analysis: 2.0 µg/mL from a representative lot detected Achaete-scute homolog 1 (ASCL1) in 5 µg of mouse E13-14 brain lysate and A549 cell lysate.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Achaete-scute homolog 1 (ASCL1) in rat cerebellum, rat cerebral cortex, and rat hippocampus tissue.
This Anti-Achaete-scute homolog 1 Antibody (ASCL1) is validated for use in Western Blotting and Immunohistochemistry for the detection of Achaete-scute homolog 1 (ASCL1).

质量

Evaluated by Western Blotting using lysate from cells over expressing Achaete-scute homolog 1 (ASCL1).

Western Blotting Analysis: 0.5 µg/mL of this antibody detected Achaete-scute homolog 1 (ASCL1) in 5 µg of lysate from cells over expressing Achaete-scute homolog 1 (ASCL1).

目标描述

~38 kDa observed

外形

Affinity purified

其他说明

Concentration: Please refer to lot specific datasheet.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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