产品介绍：
产品说明
应用
2′-Deoxyguanosine monohydrate has been used as a nucleoside supplement:
- to study its effect on mitochondrial DNA copy number in deoxyguanosine kinase (dguok) mutant zebrafish,
- in tissue culture medium for deoxyribonucleotide triphosphate (dNTP) synthesis,
- in RPMI (Roswell Park Memorial Institute)-1640 medium to eliminate the endogenous thymocytes
包装
1, 5 g in poly bottle
25, 100 mg in poly bottle
生化/生理作用
Deoxyguanosine (dG) is a purine nucleoside that upon sequential phosphorylation (kinases) forms deoxyguanosine triphosphate (dGTP) which is used by DNA polymerases and reverse transcriptases to synthesize DNA(s). Deoxyguanosine is the most electron-rich of the four canonical bases and includes many nucleophilic sites which are susceptible to oxidative damage. This makes deoxyguanosine and its oxidized derivatives useful reagents to study mechanisms of oxidative damage to nucleosides and nucleotides.
基本信息
| 经验(实验)分子式 | C10H13N5O4 · H2O |
| 分子量 | 285.26 |
| Beilstein | 39814 |
| MDL编号 | MFCD00150760 |
| PubChem化学物质编号 | 24894083 |
| NACRES | NA.51 |
产品性质
| 质量水平 | 200 |
| 生物来源 | synthetic (organic) |
| 测定 | 99-100% |
| 形式 | powder |
| 溶解性 | 1 M NH4OH: 50 mg/mL, clear, colorless |
| SMILES string | O.NC1=Nc2c(ncn2[C@H]3C[C@H](O)[C@@H](CO)O3)C(=O)N1 |
| InChI | 1S/C10H13N5O4.H2O/c11-10-13-8-7(9(18)14-10)12-3-15(8)6-1-4(17)5(2-16)19-6;/h3-6,16-17H,1-2H2,(H3,11,13,14,18);1H2/t4-,5+,6+;/m0./s1 |
| InChI key | LZSCQUCOIRGCEJ-FPKZOZHISA-N |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
