产品说明
一般描述
Lyso SM (d18:1), also known as sphingosylphosphorylcholine (SPC), is a bioactive lipid molecule. This lysophospholipid is present in normal blood plasma, ascites and various tissues.
应用
Lyso SM (d18:1) has been used:
- to study its effect on the skeletal muscle ryanodine receptor (RyR1), in the presence and absence of calmodulin through single channel recordings in planar lipid bilayers
- as an inhibitor of Ca2+ sensor calmodulin (CaM)
- as a standard in circular dichroism (CD) spectroscopy to determine lipid selectivity of the lipid-peptide interactions
生化/生理作用
Lyso SM (d18:1) or sphingosylphosphorylcholine (SPC) is a lipid mediator that exhibits second messenger functions. It regulates ryanodine receptors (RyRs) and releases Ca2+ from the sarco/endoplasmic reticulum. Lyso SM (d18:1) acts as an endogenous inhibitor of ubiquitous Ca2+ sensor calmodulin (CaM).
包装
5 mL Amber Glass Screw Cap Vial (860600P-25mg)
5 mL Amber Glass Screw Cap Vial (860600P-50mg)
5 mL Amber Glass Screw Cap Vial (860600P-5mg)
5 mL Amber Glass Screw Cap Vial (860600P-10mg)
基本信息
经验(实验)分子式 | C23H49N2O5P |
分子量 | 464.62 |
NACRES | NA.25 |
产品性质
形式 | powder |
包装 | pkg of 1 × 10 mg (860600P-10mg) pkg of 1 × 25 mg (860600P-25mg) pkg of 1 × 5 mg (860600P-5mg) pkg of 1 × 50 mg (860600P-50mg) |
manufacturer/tradename | Avanti Polar Lipids 860600P |
运输 | dry ice |
储存温度 | −20℃ |
SMILES string | [H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(N)COP([O-])(OCC[N+](C)(C)C)=O |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |