产品说明
一般描述
Chemical structure: peptide
应用
Actinonin has been used as a control to inhibit meprin-β activity in C57BL/6 mice. It has also been used to study the high-affinity interaction of EcPDF with actinonin by 15N NMR spectroscopy and isothermal titration.
包装
10 mg in glass bottle
25 mg in poly bottle
生化/生理作用
Actinonin has inhibitory action against peptide deformylase (PDF). It is effective against Gram-positive and fastidious Gram-negative microorganisms.
Actinonin is an inhibitor of leucine aminopeptidase. Actinonin has also been used to improve antibacterial activity and antiobesity therapeutics.
特点和优势
This compound is featured on the Neuropeptidases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
基本信息
| 经验(实验)分子式 | C19H35N3O5 |
| 分子量 | 385.50 |
| Beilstein | 1555250 |
| MDL编号 | MFCD00080257 |
| PubChem化学物质编号 | 24278232 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 200 |
| 生物来源 | synthetic (organic) |
| 测定 | ≥98% (TLC) |
| 形式 | powder |
| 溶解性 | ethanol: 50 mg/mL, clear, colorless |
| 作用机制 | enzyme | inhibits |
| 抗生素抗菌谱 | Gram-negative bacteria Gram-positive bacteria |
| 储存温度 | −20℃ |
| SMILES string | CCCCCC(CC(=O)NO)C(=O)NC(C(C)C)C(=O)N1CCCC1CO |
| InChI | 1S/C19H35N3O5/c1-4-5-6-8-14(11-16(24)21-27)18(25)20-17(13(2)3)19(26)22-10-7-9-15(22)12-23/h13-15,17,23,27H,4-12H2,1-3H3,(H,20,25)(H,21,24) |
| InChI key | XJLATMLVMSFZBN-UHFFFAOYSA-N |
| Gene Information | human ... ANPEP(290), DPP4(1803), ECE1(1889), LAP3(51056) |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
