产品介绍：
产品说明
应用
(R)-(+)-8-Hydroxy-DPAT hydrobromide has been used as a 5-HT1A agonist:
- in mice to test the activity of the serotonin receptor
- to test its effect on zebrafish melanocyte migration and survival
- to stimulate hippocampal neurons
包装
5, 25, 100 mg in glass bottle
生化/生理作用
(R)-(+)-8-Hydroxy-DPAT administration reduces aggressive behavior. It decreases food intake by modifying the sensitivity of 5-HT1A receptor during food deprivation.
(R)-(+)-8-Hydroxy-DPAT is a full 5-HT1A serotonin receptor agonist; active enantiomer of (±)-8-hydroxy-DPAT.
基本信息
| 经验(实验)分子式 | C16H25NO · HBr |
| 分子量 | 328.29 |
| MDL编号 | MFCD00153810 |
| PubChem化学物质编号 | 24278480 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | solid |
| 旋光性 | [α]25/D +68.2°, c = 1 in methanol(lit.) |
| 储存条件 | protect from light |
| 颜色 | white to off-white |
| 溶解性 | H2O: >10 mg/mL at ±60 ℃ (with sonication) |
| SMILES string | Br.CCCN(CCC)[C@@H]1CCc2cccc(O)c2C1 |
| InChI | 1S/C16H25NO.BrH/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14;/h5-7,14,18H,3-4,8-12H2,1-2H3;1H/t14-;/m1./s1 |
| InChI key | BATPBOZTBNNDLN-PFEQFJNWSA-N |
| Gene Information | human ... HTR1A(3350) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
