产品说明
应用
R-(−)-Fluoxetine hydrochloride has been used as a serotonin reuptake inhibitor:
- to study its effects on the embryoid body (EB) morphogenesis
- in combination with muscimol hydrobromide (MUS) as well as individually to study its neurotoxic effects on neuronal cells grown on multielectrode array (MEA) chips
- to study its effects as an endocrine disruption inducer in Pimephales promelas
包装
5, 25 mg in glass bottle
生化/生理作用
Fluoxetine exhibits anti-depressant activity by increasing the serotonin levels in the neuron synaptic space. It also exhibits therapeutic effects against depression and other mood disorders.
Selective serotonin reuptake inhibitor.
特点和优势
This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
基本信息
经验(实验)分子式 | C17H18NOF3 · HCl |
分子量 | 345.79 |
MDL编号 | MFCD04040065 |
PubChem化学物质编号 | 24278433 |
NACRES | NA.77 |
产品性质
质量水平 | 100 |
测定 | >98% (HPLC) |
形式 | solid |
颜色 | white |
溶解性 | H2O: soluble >10 mg/mL |
创始人 | Eli Lilly |
SMILES string | Cl[H].CNCC[C@@H](Oc1ccc(cc1)C(F)(F)F)c2ccccc2 |
InChI | 1S/C17H18F3NO.ClH/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20;/h2-10,16,21H,11-12H2,1H3;1H/t16-;/m1./s1 |
InChI key | GIYXAJPCNFJEHY-PKLMIRHRSA-N |
Gene Information | human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2B(3357), HTR2C(3358), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242), HTR4(3360), HTR5A(3361), HTR5B(645694), HTR6(3362), HTR7(3363) |
安全信息
象形图 | |
警示用语: | Danger |
危险声明 | H302 - H315 - H318 |
预防措施声明 | P280 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 + P310 |
危险分类 | Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 |
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |