产品说明
包装
5, 25 mg in glass bottle
生化/生理作用
NS5806 increases peak current amplitude of the potassium channel Kv4.3 (EC50 = 5.3 uM). NS5806 also slows Kv4.3 and Kv4.2 current dacay in channel complexes containing KChIP2. In ventricular cardiomycytes, NS5806 increases transient outward current and reproduces the electrocardiographic profile of Brugada syndrome.
基本信息
经验(实验)分子式 | C16H8Br2F6N6O |
分子量 | 574.07 |
MDL编号 | MFCD18432708 |
PubChem化学物质编号 | 329818416 |
NACRES | NA.77 |
产品性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | powder |
颜色 | white to faint yellow |
溶解性 | DMSO: >30 mg/mL |
储存温度 | 2-8℃ |
SMILES string | FC(F)(F)c1cc(NC(=O)Nc2c(Br)cc(Br)cc2-c3nnn[nH]3)cc(c1)C(F)(F)F |
InChI | 1S/C16H8Br2F6N6O/c17-8-4-10(13-27-29-30-28-13)12(11(18)5-8)26-14(31)25-9-2-6(15(19,20)21)1-7(3-9)16(22,23)24/h1-5H,(H2,25,26,31)(H,27,28,29,30) |
InChI key | UZWJWROOLOOCPQ-UHFFFAOYSA-N |
安全信息
象形图 | |
警示用语: | Danger |
危险声明 | H301 - H413 |
预防措施声明 | P273 - P301 + P310 + P330 |
危险分类 | Acute Tox. 3 Oral - Aquatic Chronic 4 |
储存分类代码 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |