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n-Amyl 2-[3,5-dihydroxy-2-(1-nonanoyl)phenyl]acetate

品牌
Sigma-Aldrich
货号
A0987
规格纯度
≥98% (HPLC)
参考价格
1682.59 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

n-Amyl 2-[3,5-dihydroxy-2-(1-nonanoyl)phenyl]acetate is a Nur77 agonist. Nur77 is a steroid orphan receptor that plays a critical role in regulating proliferation, differentiation and apoptosis. n-Amyl 2-[3,5-dihydroxy-2-(1-nonanoyl)phenyl]acetate, a cytosporone B analog, is a stronger activator of Nur77 than it parent compound. n-Amyl 2-[3,5-dihydroxy-2-(1-nonanoyl)phenyl]acetate treatment causes Nur77 migration to mitochondria, which results in mitochondrial Cyt c release into the cytoplasm and mitochondrial AIF redistribution in both the cytoplasm and nucleus.

特点和优势

This compound is featured on the Nuclear Receptors (Non-Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式C22H34O5
分子量378.50
MDL编号MFCD18632550
PubChem化学物质编号329770645

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 white
溶解性DMSO: >65 mg/mL
储存温度2-8℃
SMILES stringCCCCCCCCC(=O)c1c(O)cc(O)cc1CC(=O)OCCCCC
InChI1S/C22H34O5/c1-3-5-7-8-9-10-12-19(24)22-17(14-18(23)16-20(22)25)15-21(26)27-13-11-6-4-2/h14,16,23,25H,3-13,15H2,1-2H3
InChI keyFCKDHZVFIMRCNM-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
危险分类Acute Tox. 4 Oral
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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