WS3

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

WS3 is a non-cell specific proliferative molecule, thought to act primarily through modulating the activity of ErbB3-binding protein 1 (EBP1) also known as proliferation-associated protein 2G4 (PA2G4), an RNA-binding protein that is involved in growth regulation and inhibition. It may alsohae some activity through the I?B kinase pathway. WS3 was initially found to be a proliferative molecule for β-cells, but more recently found to mediate proliferation of primary retinal pigment epithelial cells. After W3 removal, the retinal cells differentiated into a functional monolayer and remained functional in vivo, preserving vision when they were transplanted into RCS rats used as a model of retinal degeneration.

特点和优势

This compound is featured on the EGFR page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

产品性质

安全信息