产品介绍：
产品说明
生化/生理作用
ST034307 is a selective inhibitor of adenylyl cyclase 1 (AC1) with analgesic activity. Adenylyl cyclase 1 has been shown to be a potential target for treating pain and reducing the dependency on opioids, but it has been difficult to inhibit AC1 selectively without also inhibiting other isoforms vital to physiological functions. ST034307 is selective for AC1 over all eight other adenylyl cyclase isoforms. It inhibited AC1 and reduced cAMP, while leaving AC8 unaffected and was shown to reduce pain in a mouse inflammatory pain model.
基本信息
| 经验(实验)分子式 | C10H4Cl4O2 |
| 分子量 | 297.95 |
| MDL编号 | MFCD00760793 |
| NACRES | NA.77 |
产品性质
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 颜色 | faint green to dark gray |
| 溶解性 | DMSO: 2 mg/mL, clear (warmed) |
| 储存温度 | −20℃ |
| SMILES string | ClC(Cl)(Cl)C1=CC(C2=CC(Cl)=CC=C2O1)=O |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
