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N-Desethyl sunitinib hydrochloride

品牌
Sigma-Aldrich
CAS
356068-97-8
货号
SML3117
规格纯度
≥98% (HPLC)
参考价格
1272.2 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

生化/生理作用

N-Desethyl sunitinib is a multi-target tyrosine kinase inhibitor that is a major active metabolite of an anticancer drug sunitinib. N-Desethyl sunitinib has a similar kinase inhibitory effect as sunitinib. In patients, plasma sunitinib and N-desethyl sunitinib accounts for 42% and 24%, respectively. Thus N-desethyl sunitinib accounts for one third of the therapeutic effect of oral sunitinib.

基本信息

经验(实验)分子式C20H23FN4O2 · xHCl
分子量370.42 (free base basis)
MDL编号MFCD18252482

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
储存条件desiccated
颜色 white to beige
溶解性DMSO: 2 mg/mL, clear (warmed)
储存温度2-8℃

安全信息

象形图GHS08GHS09
警示用语:Warning
危险声明H361d - H373 - H410
预防措施声明P202 - P260 - P273 - P280 - P308 + P313 - P391
危险分类Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 2
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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