产品介绍:
产品说明
生化/生理作用
N-Desethyl sunitinib is a multi-target tyrosine kinase inhibitor that is a major active metabolite of an anticancer drug sunitinib. N-Desethyl sunitinib has a similar kinase inhibitory effect as sunitinib. In patients, plasma sunitinib and N-desethyl sunitinib accounts for 42% and 24%, respectively. Thus N-desethyl sunitinib accounts for one third of the therapeutic effect of oral sunitinib.
基本信息
经验(实验)分子式 | C20H23FN4O2 · xHCl |
分子量 | 370.42 (free base basis) |
MDL编号 | MFCD18252482 |
产品性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | powder |
储存条件 | desiccated |
颜色 | white to beige |
溶解性 | DMSO: 2 mg/mL, clear (warmed) |
储存温度 | 2-8℃ |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H361d - H373 - H410 |
预防措施声明 | P202 - P260 - P273 - P280 - P308 + P313 - P391 |
危险分类 | Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 2 |
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |