产品说明
应用
MoTP may be used in cell signaling and differentiation studies.
包装
5, 25 mg in glass bottle
生化/生理作用
MoTP (also known as 33N14) reversibly blocks the specification of neural crest cells into melanocytes in zebrafish studies. Differentiation of neural crest cell-derived melanoblasts proceeds to late developmental stages, but they fail to reach the terminal stage of melanin production and die. Melanocytotoxicity is dependent on tyrosinase activity which convert it into a toxic form. MoTP specifically ablates only cells that express tyrosinase at high levels, which in the embryo are limited to melanoblasts and newly formed melanocytes. MoTP should be a useful tool for elucidating melanocyte stem cell regeneration, recruitment, and maintenance.
基本信息
| 经验(实验)分子式 | C14H21NO2S |
| 分子量 | 267.39 |
| MDL编号 | MFCD00642470 |
| PubChem化学物质编号 | 329825117 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 颜色 | white to tan |
| 溶解性 | DMSO: ≥80 mg/mL |
| 储存温度 | −20℃ |
| SMILES string | Oc1ccc(SCCCCN2CCOCC2)cc1 |
| InChI | 1S/C14H21NO2S/c16-13-3-5-14(6-4-13)18-12-2-1-7-15-8-10-17-11-9-15/h3-6,16H,1-2,7-12H2 |
| InChI key | YHKNLUTUXZDOQI-UHFFFAOYSA-N |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
