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MoTP

品牌
Sigma-Aldrich
CAS
57055-82-0
货号
SML0047
规格纯度
≥98% (HPLC)
参考价格
932.18 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

应用

MoTP may be used in cell signaling and differentiation studies.

包装

5, 25 mg in glass bottle

生化/生理作用

MoTP (also known as 33N14) reversibly blocks the specification of neural crest cells into melanocytes in zebrafish studies. Differentiation of neural crest cell-derived melanoblasts proceeds to late developmental stages, but they fail to reach the terminal stage of melanin production and die. Melanocytotoxicity is dependent on tyrosinase activity which convert it into a toxic form. MoTP specifically ablates only cells that express tyrosinase at high levels, which in the embryo are limited to melanoblasts and newly formed melanocytes. MoTP should be a useful tool for elucidating melanocyte stem cell regeneration, recruitment, and maintenance.

基本信息

经验(实验)分子式C14H21NO2S
分子量267.39
MDL编号MFCD00642470
PubChem化学物质编号329825117
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 white to tan
溶解性DMSO: ≥80 mg/mL
储存温度−20℃
SMILES stringOc1ccc(SCCCCN2CCOCC2)cc1
InChI1S/C14H21NO2S/c16-13-3-5-14(6-4-13)18-12-2-1-7-15-8-10-17-11-9-15/h3-6,16H,1-2,7-12H2
InChI keyYHKNLUTUXZDOQI-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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