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Larazotide acetate salt

品牌
Sigma-Aldrich
货号
SML2475
规格纯度
≥95% (HPLC)
参考价格
957.62 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

生化/生理作用

Larazotide acetate (AT1001) is a Zonulin receptor antagonist, a tight junction modulator. Larazotide inhibition of zonulin results in reducing trafficking across epithelial cells in the intestines and reducing intestinal permeability and "leaky gut," thought to be a gateway to multiple autoimmune diseases, including celiac disease, irritable bowel syndrome (IBS), inflammatory bowel diseases (IBD, Crohn′s and ulcerative colitis), type 1 diabetes mellitus (T1DM), nonalcoholic steatohepatitis (NASH), chronic kidney disease (CKD) and several others. It has been shown to inhibit the effect of inflammatory cytokines such as tumor necrosis factor (TNF-alpha) and interleukin (IL-4), blocking their increase of intestinal epithelial permeability.

基本信息

经验(实验)分子式C32H55N9O10 · xC2H4O2
分子量725.83 (free base basis)

产品性质

测定≥95% (HPLC)
形式powder
颜色 white to beige
运输wet ice
储存温度−20℃

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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