位置:首页 > 品牌 > Sigma-Aldrich >

IMB5046

品牌
Sigma-Aldrich
CAS
1001571-08-9
货号
SML1903
包装型号
规格纯度
≥98% (HPLC)
参考价格
1117.23 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

IMB5046 is a microtubule inhibitor that has antitumor activity, overcoming multidrug-resistance. IMB5046 was cytotoxic with an IC50 range of 37 to 426 nM against multiple tumor cell lines, including some that were resistant to colchicine, vincristine and paclitaxel. IMB5046 was also active against human lung tumor xenografts. IMB5046 was found to bind to tubulin at the colchicine site, but with a different binding mode. IMB5046 inhibited tubulin polymerization, and induced G2/M arrest.

基本信息

经验(实验)分子式C19H20N2O5S
分子量388.44
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 white to beige
溶解性DMSO: 20 mg/mL, clear
储存温度2-8℃
SMILES stringO=C(C1=C(N2CCOCC2)C=CC([N+]([O-])=O)=C1)OCC3=CC=C(SC)C=C3

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

推荐产品
| 首页 | 联系我们 | 会员服务 | 广告服务 | 友情链接 |
版权所有 CopyRight © 2008-2024 粤ICP备08119708号