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D-NMAPPD

品牌
Sigma-Aldrich
CAS
35922-06-6
货号
SML2358
规格纯度
≥98% (HPLC)
参考价格
660.71 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

生化/生理作用

D-NMAPPD (B13), a myristoyl-CoA analog, is a cell penetrant inhibitor of N-myristoyltransferases that suppressed FRS2α (fibroblast growth factor receptor substrate 2) myristoylation. D-NMAPPD inhibits wild-type FGFRs and drug-resistant mutants (FGFRsDRM) oncogenic signaling in cancer cells. D-NMAPPD potently inhibits growth of xenograft tumors in mice. D-NMAPPD is a potent inhibitor of ceramidase that elevates endogenous ceramide levels and suppress growth of cancer cells.

基本信息

经验(实验)分子式C23H38N2O5
分子量422.56
MDL编号MFCD08062172

产品性质

测定≥98% (HPLC)
形式powder
旋光性[α]/D -28 to -34, c = 0.1 in chloroform-d
颜色 white to beige
溶解性DMSO: 2 mg/mL, clear
储存温度2-8℃

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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