产品介绍：
产品说明
应用
CASIN has been used as a cell division control protein 42 homolog (Cdc42) inhibitor:
- to study its effects on the stimulation of extracellular vesicles (EVs) in intestinal epithelial cells
- to study its effects on mice jejunum
- to study its effects on microbial adhesion-triggered endocytosis (MATE) vesicle morphology in segmented filamentous bacteria (SFB)-colonized mice
包装
5, 25 mg in glass bottle
生化/生理作用
CASIN is an inhibitor of Cdc42 GTPase, a small GTPase of the Rho-subfamily that plays important roles in cytoskeleton organization, cell cycle progression, signal transduction, and vesicle trafficking. CASIN generated a rejuvenated phenotype of Hematopoietic stem cells (HSCs), reversing the aging-related and polarity phenotype of aged HSCs to that of young HSCs in vivo..
基本信息
| 经验(实验)分子式 | C20H22N2O |
| 分子量 | 306.40 |
| MDL编号 | MFCD01853271 |
| PubChem化学物质编号 | 329825745 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 颜色 | , white to very dark brown |
| 溶解性 | DMSO: 20 mg/mL, clear |
| 储存温度 | 2-8℃ |
| SMILES string | OCCNC1CCCC2=C1NC3=C2C=C(C4=CC=CC=C4)C=C3 |
| InChI | 1S/C20H22N2O/c23-12-11-21-19-8-4-7-16-17-13-15(14-5-2-1-3-6-14)9-10-18(17)22-20(16)19/h1-3,5-6,9-10,13,19,21-23H,4,7-8,11-12H2 |
| InChI key | RXIUMAOXORBRCY-UHFFFAOYSA-N |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
