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Aurothioglucose hydrate

品牌
Sigma-Aldrich
CAS
12192-57-3
货号
A0606
规格纯度
≥96% (titration)
参考价格
1379.75 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

应用

Aurothioglucose hydrate has been used in redox stress survival assay in human cell lines and for inducing obese phenotype in mice.

包装

5, 25 mg in glass bottle

生化/生理作用

Aurothioglucose, a gold compound used clinically to treat rheumatoid arthritis, has recently been found to be a potent PKCiota-Par6 interaction inhibitor, with an IC50 approximately 1 μM. Disruption of this interaction disrupts a rac1 signaling pathway that is required for transformed growth in non-small-cell lung cancer.

特点和优势

This compound is featured on the PKC page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式C6H11AuO5S · xH2O
分子量392.18 (anhydrous basis)
EC 号235-365-7
PubChem化学物质编号24724383
NACRESNA.77

产品性质

质量水平100
测定≥96% (titration)
形式powder
储存条件desiccated
颜色 white to beige
溶解性H2O: 5 mg/mL, clear
储存温度2-8℃
SMILES stringO.OC[C@H]1O[C@H](S[Au])[C@H](O)[C@@H](O)[C@@H]1O
InChI1S/C6H12O5S.Au.H2O/c7-1-2-3(8)4(9)5(10)6(12)11-2;;/h2-10,12H,1H2;;1H2/q;+1;/p-1/t2-,3-,4+,5-,6-;;/m1../s1
InChI keySGVIEHTYEMEDRR-PKXGBZFFSA-M

安全信息

象形图GHS08
警示用语:Danger
危险声明H317 - H334
预防措施声明P261 - P280 - P342 + P311
危险分类Resp. Sens. 1 - Skin Sens. 1
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Sigma-Aldrich

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