产品介绍：
产品说明
包装
5, 25 mg in glass bottle
生化/生理作用
ASP7663 is a selective activator of transient receptor potential ankyrin 1 (TRPA1), known to play a role for chemical sensing in the pain pathway. ASP7663 activated human, rat, and mouse TRPA1 receptors with EC50 values of 510, 540, and 500 nM, respectively, and little or no affinity at more than 60 other related receptors, channels and enzymes. ASP7663 enhanced colonic motility and exerted analgesic effects against abdominal pain in mouse models.
基本信息
| 经验(实验)分子式 | C14H14FNO3 |
| 分子量 | 263.26 |
| PubChem化学物质编号 | 329825901 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 颜色 | light orange to dark orange |
| 溶解性 | DMSO: 25 mg/mL, clear |
| 储存温度 | 2-8℃ |
| SMILES string | CC(C)CN(C1=C(F)C=CC=C1/C2=C\C(O)=O)C2=O |
| InChI | 1S/C14H14FNO3/c1-8(2)7-16-13-9(4-3-5-11(13)15)10(14(16)19)6-12(17)18/h3-6,8H,7H2,1-2H3,(H,17,18)/b10-6+ |
| InChI key | RCVZUIGCNAAMIC-UXBLZVDNSA-N |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
