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Apostatin-1

品牌
Sigma-Aldrich
CAS
2559703-06-7
货号
SML3028
规格纯度
≥98% (HPLC)
参考价格
878.98 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

生化/生理作用

Apostatin-1 is a cell penetrant apoptosis inhibitor that activates autophagy leading to restoration of cellular homeostasis in cells with accumulated mutant tau, α-synuclein, or huntingtin. Apostatin-1 potently and selectively inhibits TRADD. It binds to the N-terminal TRAF2-binding domain of TRADD (TRADD-N). Apparently Apostatin-1 releases cIAP1/2 or TRAF2 from TRADD thus promoting the K63-linked ubiquitination of beclin 1.

基本信息

经验(实验)分子式C19H27N3OS
分子量345.50

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 white to beige
溶解性DMSO: 2 mg/mL, clear
储存温度2-8℃
SMILES stringO=C(C(C1=CC=CC=C1)SC2=NCCN2C)NC3CCCCCC3

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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