产品说明
一般描述
2-Bromo-1-ethyl-pyridinium tetrafluoroborate is a coupling reagent employed in the synthesis of amides and esters through amidation and esterification reactions, respectively. It is generally prepared by the reaction of triethyloxonium tetrafluoroborate with 2?bromo pyridine.
应用
2-Bromo-1-ethyl-pyridinium tetrafluoroborate can be used as a coupling reagent for:
- The synthesis of N-methylated peptides in solution and solid phase.
- The synthesis of cyclosporin A fragment and dolastatin 15 pentapeptide moiety.
包装
5 g in poly bottle
其他说明
用于肽合成的偶联试剂;与其他试剂如 BOP、PyBrOP、PyClU、BTFFH、CMBI 相比,外消旋作用更低、反应更快
基本信息
经验(实验)分子式 | C7H9BBrF4N |
分子量 | 273.86 |
Beilstein | 4059265 |
EC 号 | 212-900-2 |
MDL编号 | MFCD00060046 |
PubChem化学物质编号 | 57652696 |
NACRES | NA.22 |
产品性质
质量水平 | 100 |
测定 | ≥97.0% (T) |
reaction suitability | reaction type: Coupling Reactions |
mp | 103-107 ℃ |
application(s) | peptide synthesis |
SMILES string | F[B-](F)(F)F.CC[n+]1ccccc1Br |
InChI | 1S/C7H9BrN.BF4/c1-2-9-6-4-3-5-7(9)8;2-1(3,4)5/h3-6H,2H2,1H3;/q+1;-1 |
InChI key | YJDXVQLBIAJTHP-UHFFFAOYSA-N |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves, type N95 (US) |