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Reparixin

品牌
Sigma-Aldrich
CAS
266359-83-5
货号
SML2655
规格纯度
≥98% (HPLC)
参考价格
1399.43 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

生化/生理作用

Reparixin is a noncompetitive allosteric inhibitor of the inflammatory CXCL8 (IL-8) chemokine receptors CXCR1 and CXCR2 with IC50 values of 1 nM for CXCR1 and 100 nM for CXCR2. It is believed to prevent receptor signaling by locking CXCR1/R2 in an inactive conformation. Reparixin has been studied to prevent ischaemia-reperfusion injury and inflammation and is clinical trials for triple negative breast cancer and to prevent injury occurring after pancreatic islet transplantation.

基本信息

经验(实验)分子式C14H21NO3S
分子量283.39
MDL编号MFCD18633292

产品性质

测定≥98% (HPLC)
形式powder
旋光性[α]/D -80 to -90°, c = 1.0 in ethanol
颜色 white to beige
溶解性DMSO: 2 mg/mL, clear
储存温度−20℃
InChI1S/C14H21NO3S/c1-10(2)9-12-5-7-13(8-6-12)11(3)14(16)15-19(4,17)18/h5-8,10-11H,9H2,1-4H3,(H,15,16)
InChI keyKQDRVXQXKZXMHP-UHFFFAOYSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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