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Pimelic Diphenylamide 106

品牌
Sigma-Aldrich
CAS
937039-45-7
货号
SML0313
规格纯度
≥98% (HPLC)
参考价格
1032.8 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

Pimelic diphenylamides has the ability to enhance the expression of the frataxin gene in lymphocytes from Friedreich ataxia patients.
106 is a Class I HDAC inhibitor, demonstrating no activity against class II HDACs. It is a slow, tight-binding inhibitor of HDACs 1, 2, and 3, with a preference toward HDAC3 with Ki of 14 nM, 15 times lower than the Ki for HDAC1.

基本信息

经验(实验)分子式C20H25N3O2
分子量339.43
MDL编号MFCD17010287
PubChem化学物质编号329825318
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 white to beige
溶解性DMSO: ≥15 mg/mL
储存温度2-8℃
SMILES stringCc1ccc(NC(=O)CCCCCC(=O)Nc2ccccc2N)cc1
InChI1S/C20H25N3O2/c1-15-11-13-16(14-12-15)22-19(24)9-3-2-4-10-20(25)23-18-8-6-5-7-17(18)21/h5-8,11-14H,2-4,9-10,21H2,1H3,(H,22,24)(H,23,25)
InChI keyWTKBRPXPNAKVEQ-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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