Ozagrel hydrochloride hydrate

产品介绍：

产品说明

应用

Ozagrel hydrochloride hydrate has been used as a thromboxane synthase inhibitor:

in high cholesterol-diet rats (HC) to test its effect on arteriolar constriction
to pre-treat mice to test its effect on lipopolysaccharide (LPS)-induced behavioral changes
to test its effect on arteriolar vasoconstriction in hyperglycemic mice

包装

5, 25 mg in glass bottle

生化/生理作用

Ozagrel is useful in treating lacunar and thrombotic stroke. It blocks vasoconstriction and platelet aggregation. Ozagrel aids in improving the prostacyclin (PGI2)/ thromboxane A2 (TXA2) in the acute phase of cerebral ischemia. It improves endothelial dysfunction in L-methionine-induced hyperhomocysteinemia (HHcy)-induced vascular cognitive impairment and dementia (VCID).
Ozagrel is a selective thromboxane A₂ synthase (TXA₂) inhibitor.

基本信息

经验(实验)分子式	C₁₃H₁₂N₂O₂ · HCl · xH₂O
分子量	264.71 (anhydrous basis)
MDL编号	MFCD00911569
PubChem化学物质编号	24897942
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	solid
颜色	white to off-white
溶解性	H₂O: soluble
储存温度	room temp
SMILES string	O.Cl.OC(=O)\C=C\c1ccc(Cn2ccnc2)cc1
InChI	1S/C13H12N2O2.ClH.H2O/c16-13(17)6-5-11-1-3-12(4-2-11)9-15-8-7-14-10-15;;/h1-8,10H,9H2,(H,16,17);1H;1H2/b6-5+;;
InChI key	OWIZTYOMGVTSDP-TXOOBNKBSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)