产品介绍：
产品说明
包装
5, 25 mg in glass bottle
生化/生理作用
Gemifloxacin is a broad-spectrum quinolone antibacterial. Fluoroquinolones stabilize DNA strand breaks created by DNA gyrase and topoisomerase IV by binding to the enzyme-DNA complex generating persistent, covalent enzyme–DNA adducts, inhibiting DNA synthesis. Gemifloxacin is used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia. Gemifloxacin has also been found to inhibit migration and invasion of human colon cancer cells.
基本信息
| 经验(实验)分子式 | C18H20FN5O4 · CH4O3S |
| 分子量 | 485.49 |
| MDL编号 | MFCD08277637 |
| PubChem化学物质编号 | 329825509 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 颜色 | white to light brown |
| 溶解性 | H2O: 10 mg/mL, clear |
| 储存温度 | room temp |
| SMILES string | CS(=O)(O)=O.OC(C1=CN(C2CC2)C3=NC(N4C/C(C(CN)C4)=N\OC)=C(F)C=C3C1=O)=O |
| InChI | 1S/C18H20FN5O4.CH4O3S/c1-28-22-14-8-23(6-9(14)5-20)17-13(19)4-11-15(25)12(18(26)27)7-24(10-2-3-10)16(11)21-17;1-5(2,3)4/h4,7,9-10H,2-3,5-6,8,20H2,1H3,(H,26,27);1H3,(H,2,3,4)/b22-14+; |
| InChI key | JIYMVSQRGZEYAX-CWUUNJJBSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H341 - H361d - H373 |
| 预防措施声明 | P202 - P260 - P280 - P308 + P313 - P405 - P501 |
| 危险分类 | Muta. 2 - Repr. 2 - STOT RE 2 |
| 靶器官 | Liver |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
