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Eicosapentaenoyl ethanolamide

品牌
Sigma-Aldrich
CAS
109001-03-8
货号
SML0384
规格纯度
5 mg/mL in absolute ethanol, ≥98% (HPLC)
参考价格
1203.82 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

Eicosapentaenoyl ethanolamide (EPEA) is a lipid mediator that has been found to suppress lifespan extension resulting from dietary restriction in C. elegans and also to have antiproliferative and anti-inflammatory actions. In C. elegans, it is believed to act as a metabolic signal that couples nutrient availability with growth and lifespan. EPEA is a member of the N-acylethanolamines (NAEs), lipid-derived signaling molecules that include the mammalian endocannabinoid arachidonoyl ethanolamide (AEA). In mammals, NAEs are believed to act primarily through cannabinoid receptors, although they can also interact with a variety of other targets, and EPEA has been shown to act as a CB1 and CB2 receptor agonist. However, C. elegans does not possess clear orthologues of the mammalian cannabinoid receptors which suggests that there are unidentified NAE receptors in nematodes that are possibly conserved mediators of NAE signaling.

其他说明

Light and air sensitive; store in a freezer.

基本信息

经验(实验)分子式C22H35NO2
分子量345.52
MDL编号MFCD22416528
PubChem化学物质编号329825384
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式solution
drug controlregulated under CDSA - not available from sigma-aldrich Canada
储存条件protect from light
under inert gas
浓度5 mg/mL in absolute ethanol
颜色light yellow
储存温度−20℃
SMILES stringCC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCCO
InChI1S/C22H35NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22(25)23-20-21-24/h3-4,6-7,9-10,12-13,15-16,24H,2,5,8,11,14,17-21H2,1H3,(H,23,25)/b4-3-,7-6-,10-9-,13-12-,16-15-
InChI keyOVKKNJPJQKTXIT-JLNKQSITSA-N

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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