产品介绍：
产品说明
包装
5, 25 mg in glass bottle
生化/生理作用
CYM-5442 is a highly-selective S1P1 (Spingosine 1-Phosphate Receptor 1) agonist that activates S1P1-dependent pathways in vitro and to levels of full efficacy in vivo through a hydrophobic pocket, separable from the orthosteric site of S1P binding that is headgroup dependent. This is a different site from those involved in the activities of other agonists such as FTY720 and SEW2871.
基本信息
| 经验(实验)分子式 | C23H27N3O4 |
| 分子量 | 409.48 |
| MDL编号 | MFCD12912402 |
| PubChem化学物质编号 | 329774920 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 溶解性 | DMSO: >5 mg/mL |
| 储存温度 | −20℃ |
| SMILES string | CCOc1ccc(cc1OCC)-c2nc(no2)-c3cccc4C(CCc34)NCCO |
| InChI | 1S/C23H27N3O4/c1-3-28-20-11-8-15(14-21(20)29-4-2)23-25-22(26-30-23)18-7-5-6-17-16(18)9-10-19(17)24-12-13-27/h5-8,11,14,19,24,27H,3-4,9-10,12-13H2,1-2H3 |
| InChI key | NUIKTBLZSPQGCP-UHFFFAOYSA-N |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
